کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2539350 | 1122173 | 2011 | 4 صفحه PDF | دانلود رایگان |

The performance of a clinical trial for pharmaceutical agents is usually undertaken only after there is likely benefit demonstrated from the use of the putative agent. The consideration of botanical products as pharmaceutical agents must similarly go through a rigorous evaluation process. The present work reviews the recently published phase II study evaluating the effectiveness of black cohosh and red clover in a randomized trial with conjugated equine estradiol/medroxyprogesterone acetate and placebo for the treatment of menopausal symptoms. We analyze the possible reasons why this study failed to show benefit for either botanical product in reducing menopause-related vasomotor symptoms.
A rigorous study of black cohosh and red clover demonstrates no clinical benefit with either botanical supplement. This paper details how a well-performed study can fail to show benefit.Figure optionsDownload as PowerPoint slide
Journal: Fitoterapia - Volume 82, Issue 1, January 2011, Pages 88–91