کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2539557 | 1559664 | 2007 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hepatoprotective activity of Calotropis procera flowers against paracetamol-induced hepatic injury in rats
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Hepatoprotective activity of Calotropis procera flowers against paracetamol-induced hepatic injury in rats Hepatoprotective activity of Calotropis procera flowers against paracetamol-induced hepatic injury in rats](/preview/png/2539557.png)
چکیده انگلیسی
Hydro-ethanolic extract (70%) of Calotropis procera flowers was prepared and tested for its hepatoprotective effect against paracetamol-induced hepatitis in rats. Alteration in the levels of biochemical markers of hepatic damage like SGPT, SGOT, ALP, bilirubin, cholesterol, HDL and tissue GSH were tested in both treated and untreated groups. Paracetamol (2 g/kg) has enhanced the SGPT, SGOT, ALP, bilirubin and cholesterol levels and reduced the serum levels of HDL and tissue level of GSH. Treatment with hydro-ethanolic extract of C. procera flowers (200 mg/kg and 400 mg/kg) has brought back the altered levels of biochemical markers to the near normal levels in the dose dependent manner.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 78, Issues 7–8, December 2007, Pages 451–454
Journal: Fitoterapia - Volume 78, Issues 7–8, December 2007, Pages 451–454
نویسندگان
S. Ramachandra Setty, Absar Ahmed Quereshi, A.H.M. Viswanath Swamy, Tushar Patil, T. Prakash, K. Prabhu, A. Veeran Gouda,