کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2540098 1122217 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Relaxant effect of aqueous extract of Cistus ladaniferus on rodent intestinal contractions
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Relaxant effect of aqueous extract of Cistus ladaniferus on rodent intestinal contractions
چکیده انگلیسی

The effects of the aqueous extract of Cistus ladaniferus leaves and stems were studied on the rodent isolated jejunum. The extract produced a reversible concentration dose-dependent (0.1–3 mg/ml) inhibition of the spontaneous motility of the rabbit jejunum. The inhibitory effects of the extract were not affected by pretreatment with the inhibitors of the α and β adrenergic receptors yohimbine, prazosin or propranolol. The extract also inhibited K+-induced contractions in rabbit and rat jejunum at a similar concentration range. This result suggests that the antispasmodic action of the extract is mediated through calcium channel blockade. The results confirm the traditional use of C. ladaniferus in treating intestinal ache.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 77, Issue 6, September 2006, Pages 425–428
نویسندگان
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