کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2586871 | 1130912 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effect of heating on peroxynitrite scavenging capacity of garlic
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کلمات کلیدی
DTPASACS-allylcysteineNDGADHR 123HRGHGPDMSO - DMSOO2− - O2-ONOO− - ONOO-superoxide anion - آنیون سوپر اکسیدnordihydroguaiaretic acid - اسید نوردی هیدروگالیارتیdihydrorhodamine 123 - دی هیدرو رودامین 123Dimethyl sulfoxide - دیمتیل سولفواکسیدHydroxyl radicals - رادیکالهای هیدروکسیلScavenging - سوزاندنGarlic - سیرPeroxynitrite - پروکسی نیتریت
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش تغذیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The ability to scavenge peroxynitrite (ONOOâ) was studied in the following aqueous garlic extracts: (a) unheated extract of garlic powder (GP), (b) heated extract of garlic powder (HGP), (c) unheated extract of raw garlic (RG), (d) heated extract of raw garlic (HRG), (e) extract of boiled garlic cloves (BG), (f) extract of microwave-treated garlic cloves (MG), and (g) extract of pickled garlic (PG). All the extracts scavenged ONOOâ in a concentration-dependent way. IC50 (mg/mL) values for each extract were 0.30 ± 0.02 and 0.35 ± 0.04 for GP and HGP, respectively; and 0.84 ± 0.08, 0.59 ± 0.04, 0.76 ± 0.09, 1.71 ± 0.19, and 1.45 ± 0.07 for RG, HRG, BG, MG, and PG, respectively. The ONOOâ scavenging capacity (IC50 values) was not decreased in HGP (vs. GP, p > 0.05) and in HRG and BG (p > 0.05 vs. RG). In contrast, the ONOOâ scavenging capacity decreased in MG and PG (vs. RG, p < 0.001). The IC50 values for the reference compounds nordihydroguiaretic acid and penicillamine were 1.1 and 4.5 μg/mL. The heating before or after garlic cutting was unable to eliminate the capacity of the extracts to scavenge ONOOâ; this capacity was significantly decreased in PG and MG.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food and Chemical Toxicology - Volume 45, Issue 4, April 2007, Pages 622-627
Journal: Food and Chemical Toxicology - Volume 45, Issue 4, April 2007, Pages 622-627
نویسندگان
José Pedraza-ChaverrÃ, Omar Noel Medina-Campos, Sabina Segoviano-Murillo,