کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2611938 | 1562876 | 2009 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Traitement nutritionnel du grand brûlé
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب اورژانس
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چکیده انگلیسی
Major burns (>20% BSA) cause an intense oxidative stress, metabolic alterations and an inflammatory response which are characterized by their intensity and duration, which exceeds those observe in all other pathologies. Modulation of these responses has become a therapeutic target. Burned patients required large amounts of energy (35-50Â kcal/kg/day), glucose and proteins (1.5-2.5Â g/kg/day) but limited amounts of fat (ideally less than 20% of total energy intake). Glutamine supplementations contribute to the normalization of the immune response and to improved wound healing. The enteral route (gastric or postpyloric) is to be preferred, and feeding should be initiated within hours of the injury. Acute and early deficits of micronutrients are caused by large exudative losses through the burn wounds. Substitution has significant biological and clinical benefits: the doses correspond to 5-10 times those used in parenteral nutrition and must be delivered for 7 to 30Â days depending on burn size. Insulin which favors anabolism, and propranolol which attenuates catabolism belong to the standard therapeutic tools. Nutritional follow up is mandatory and is based on daily body weight, and weekly determination of prealbumin.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Réanimation - Volume 18, Issue 8, December 2009, Pages 694-701
Journal: Réanimation - Volume 18, Issue 8, December 2009, Pages 694-701
نویسندگان
M.M. Berger, Y.A. Que,