Osteopathic treatment in patients with primary dysmenorrhoea: A randomised controlled trial

ObjectivesTo investigate the effectiveness of a series of osteopathic treatments in patients with pain due to primary dysmenorrhoea.Design and settingsMulti-centered randomised controlled trial with an osteopathic intervention group and an untreated (“waiting list”) control group.SubjectsWomen aged 14 years and older with a regular menstrual cycle, diagnosed with primary dysmenorrhoea.InterventionSix osteopathic treatments over a period of three menstrual cycles or no osteopathic treatment. At each treatment session, dysfunctional structures were tested and treated based on osteopathic principles. In both groups, pain medication on demand was allowed, but was documented.Outcome measuresPrimary outcome measures were average pain intensity (API) during menstruation, assessed by the Numeric Rating Scale (NRS), and days of dysmenorrhoeal pain exceeding 50% of NRS maximum (DDP). Main secondary outcome measure was health-related quality of life.ResultsA total of 60 individuals (average age 33 years) were randomised, seven patients dropped out. API decreased in the intervention group from 4.6 to 1.9 (95%CI = −1.9 to −3.5), and from 4.3 to 4.2 in controls (95%CI = −0.7 to 0.5); between group difference of means (BGDoM): 2.6, 95%CI = 1.7 to 3.6; p < 0.005. DDP decreased from 2.2 to 0.2 days in the intervention group (95%CI = −2.5 to −1.3), and from 2.3 to 1.9 in controls (95%CI = −1.0 to 0.2); BGDoM 1.5; 95%CI = 0.6 to 2.3; p = 0.002. A positive impact on quality of life (physical component score) could be observed in the osteopathic treatment group only.ConclusionsA series of osteopathic treatments might be beneficial for women suffering from primary dysmenorrhoea.