کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2629531 | 1136579 | 2009 | 6 صفحه PDF | دانلود رایگان |
SummaryObjectivesTo investigate the anti-fatigue effects of Myelophil, an extract of a mix of Astragali Radix and Salviae Radix, which has been used to treat patients with chronic fatigue.Subjects and designA randomised, double-blind, controlled clinical trial was performed with 36 adults who complained of chronic fatigue. The subjects were divided among a control group and low- and high-dose groups (3 or 6 g of oral Myelophil per day, respectively) and were monitored for 4 weeks. Fatigue severity was subjectively characterised, and the expression of 42 cytokines was evaluated using an antibody array.ResultsMyelophil administration (3 g per day) significantly decreased the fatigue severity score compared with the control (p < 0.05). No changes were noted in cytokine expression.ConclusionsMyelophil appears to have a pharmacological effect against fatigue, suggesting the clinical relevance of the traditional medicinal plants, Astragalus membranaceus and Salvia miltiorrhiza.
Journal: Complementary Therapies in Medicine - Volume 17, Issue 3, June 2009, Pages 141–146