Homeopathic treatment of minor aphthous ulcer: a randomized, placebo-controlled clinical trial

ObjectiveThe objectives of this study were to clinically determine the efficacy of individualised homeopathy in the treatment of minor recurrent aphthous ulceration (MiRAU).Design & interventionA randomized, single blind, placebo-controlled clinical trial of individualised homeopathy. One hundred patients with minor aphthous ulcer were treated with individualised homeopathic medicines or placebo and followed up for 6 days. Patients received two doses of individualised homeopathic medicines in the 6C potency as oral liquid at baseline and 12 h later. Pain intensity and ulcer size were recorded at baseline during and at the end of the trial (mornings of days 4 and 6).ResultAll 100 patients completed treatment. Between group differences for pain intensity and ulcer size were statistically significant at day 4 and at day 6 (P < 0.05). No adverse effects were reported.ConclusionThe results suggest that homeopathic treatment is an effective and safe method in the treatment of MiRAU.