کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2651388 | 1139454 | 2012 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The predictive value of plasma cystatin C for acute coronary syndrome treated with percutaneous coronary intervention The predictive value of plasma cystatin C for acute coronary syndrome treated with percutaneous coronary intervention](/preview/png/2651388.png)
BackgroundThis study was designed to evaluate the value of plasma cystatin C in predicting adverse cardiac events after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS).MethodsA total of 605 patients (404 male, mean age 60.4 ± 10.6 years) with ACS underwent successful PCI. Patients were divided into 4 groups according to the level of cystatin C, which was measured before the PCI: Q1 (<1.02 mg/L), Q2 (1.02-1.16 mg/L), Q3 (1.17-1.34 mg/L), and Q4 (≥1.35 mg/L).ResultsAfter a follow-up of 14.3 ± 1.7 months, the incidence of mortality, nonfatal myocardial infarction, and target lesion revascularization in the Q2, Q3, and Q4 groups was higher than in the Q1 group (P < .001). The incidence of heart failure in the Q3 and Q4 groups was higher than in the Q1 group (P < .05). Multivariate Cox regression analysis showed that cystatin C elevation was an independent predictor of major adverse cardiac events. The cumulative survival rate of the Q3 and Q4 groups was lower than in the Q1 group (P < .001).ConclusionHigh plasma cystatin C concentration is an independent predictor of major adverse cardiac events in patients with ACS treated with PCI.
Journal: Heart & Lung: The Journal of Acute and Critical Care - Volume 41, Issue 5, September–October 2012, Pages 456–462