کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2657421 1140012 2011 10 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله ISI
Green Tea Catechins Decrease Total and Low-Density Lipoprotein Cholesterol: A Systematic Review and Meta-Analysis
ترجمه فارسی عنوان
کلسترول چای سبز کلسترول لیپوپروتئین کل و کم چربی را کاهش می دهد: یک بررسی منظم و متاآنالیز
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
چکیده انگلیسی

Green tea catechins (GTCs) have been studied in randomized control trials for their lipid-lowering effects. Studies, however, have been small and demonstrated conflicting results. The objective of this study was to perform a systematic review and meta-analysis of randomized controlled trials evaluating the relationship between GTCs and serum lipid levels, including total, low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, and triglycerides. A systematic literature search of MEDLINE, EMBASE, Cochrane CENTRAL, and the Natural Medicines Comprehensive Database was conducted through March 2010. Randomized controlled trials evaluating GTCs vs control in human beings and reporting efficacy data on at least one of the aforementioned serum lipid endpoints were included. Weighted mean differences for changes from baseline (with 95% confidence intervals [CIs]) for lipid endpoints were calculated using random-effects models. Twenty trials (N=1,415) met all inclusion criteria. Upon meta-analysis, GTCs at doses ranging from 145 to 3,000 mg/day taken for 3 to 24 weeks reduced total (−5.46 mg/dL [−0.14 mmol/L]; 95% CI −9.59 to −1.32) and LDL cholesterol (−5.30 mg/dL [−0.14 mmol/L]; 95% CI −9.99 to −0.62) compared to control. GTCs did not significantly alter HDL cholesterol (−0.27 mg/dL [−0.007 mmol/L]; 95% CI −1.62 to 1.09) or triglyceride (3.00 mg/dL [−0.034 mmol/L]; 95% CI −2.73 to 8.73) levels. The consumption of GTCs is associated with a statistically significant reduction in total and LDL cholesterol levels; however, there was no significant effect on HDL cholesterol or triglyceride levels.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Dietetic Association - Volume 111, Issue 11, November 2011, Pages 1720–1729
نویسندگان
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