The Challenges of Oral Agents as Antineoplastic Treatments

ObjectivesGiven the increasing use of oral antineoplastic agents in cancer management, patient adherence is critical to successful treatment outcomes. This article reviews the scope of the problem and issues of adherence to oral antineoplastic agents.Data SourcesResearch-based and other articles, newsletters, and conference presentations.ConclusionSuboptimal adherence to oral antineoplastic agents is a significant clinical problem that may result in disease or treatment complications, adjustment in treatment regimen, disease progression, and premature death.Implications for Nursing PracticeHealthcare providers need to monitor and facilitate adherence by identifying barriers and implementing strategies to assure adherence, and therefore, improve clinical outcomes.