Molecular Diagnostic Testing in Breast Cancer

ObjectivesAn overview of molecular tests used in the treatment of breast cancer, organized by stage and clinical condition.Data SourcesSystematic review of scientific literature, guideline recommendations, and data published by test manufacturers.ConclusionSeveral molecular tests that analyze expression of cancer-related genes have been validated in clinical trials and are recommended by clinical practice guidelines to inform diagnosis and treatment decisions for personalized interventions.Implications for Nursing PracticeMolecular testing has become an important part of patient care for those with breast cancer. Oncology nurses must understand this methodology to prescribe tests, interpret the results, and provide guidance to patients.