Genetic Biomarkers of Cancer Risk

ObjectivesTo provide a review of genetic biomarkers of cancer risk and associated clinical implications.Data SourcesPublished literature, evidence-based guidelines.ConclusionIdentification of the genetic variation associated with cancer risk enables the health care provider to stratify an individual's risk and personalize their cancer risk management. This may lead to a decreased cancer incidence in high-risk populations, but at a minimum, will provide the opportunity for early diagnosis that may decrease cancer morbidity and mortality.Implications for Nursing PracticeNursing implications include assessment for cancer risk, initiate referrals indicated, and delivering ongoing education and support for cancer risk management plans.