Lowering HbA1c in type 2 diabetics results in reduced risk of coronary heart disease and all-cause mortality

AimsTo assess to which extent lowering the level of HbA1c influences the 10-year risk of coronary heart disease (CHD) and all-cause mortality in patients with type 2 diabetes mellitus.MethodsA literature search in Pubmed and Embase was performed, and the absolute risks in the results of the relevant and valid studies compared.ResultsEach study shows that with a decreasing percentage of HbA1c, both the risk of developing CHD and the risk of mortality decrease.ConclusionsLowering HbA1c in type 2 diabetics decreases the absolute risk of developing CHD by 5–17%, as well as decreasing all-cause mortality by 6–15%.