کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2693161 1143506 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A preliminary investigation into the effects of ocular lubricants on higher order aberrations in normal and dry eye subjects
ترجمه فارسی عنوان
یک بررسی اولیه در مورد اثرات نرم کننده چشمی در انحرافات مرتبه بالاتر در افراد نرمال و خشک چشم
کلمات کلیدی
خشکی چشم؛ روان کننده ها؛ منحنی های مرتبه بالا
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی چشم پزشکی
چکیده انگلیسی

PurposeTo study the effects of ocular lubricants on higher order aberrations in normal and self-diagnosed dry eyes.MethodsUnpreserved hypromellose drops, Tears Again™ liposome spray and a combination of both were administered to the right eye of 24 normal and 24 dry eye subjects following classification according to a 5 point questionnaire. Total ocular higher order aberrations, coma, spherical aberration and Strehl ratios for higher order aberrations were measured using the Nidek OPD-Scan III (Nidek Technologies, Gamagori, Japan) at baseline, immediately after application and after 60 min. The aberration data were analyzed over a 5 mm natural pupil using Zernike polynomials. Each intervention was assessed on a separate day and comfort levels were recorded before and after application. Corneal staining was assessed and product preference recorded after the final measurement for each intervention.ResultsHypromellose drops caused an increase in total higher order aberrations (p = <0.01 in normal and dry eyes) and a reduction in Strehl ratio (normal eyes: p = <0.01, dry eyes p = 0.01) immediately after instillation. There were no significant differences between normal and self-diagnosed dry eyes for response to intervention and no improvement in visual quality or reduction in higher order aberrations after 60 min. Differences in comfort levels failed to reach statistical significance.ConclusionCombining treatments does not offer any benefit over individual treatments in self-diagnosed dry eyes and no individual intervention reached statistical significance. Symptomatic subjects with dry eye and no corneal staining reported an improvement in comfort after using lubricants.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Contact Lens and Anterior Eye - Volume 37, Issue 2, April 2014, Pages 106–110
نویسندگان
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