کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2697400 | 1143906 | 2006 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Evaluation of povidone-iodine as a disinfectant solution for contact lenses: Antimicrobial activity and cytotoxicity for corneal epithelial cells
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
چشم پزشکی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Povidone-iodine (PVP-I) possesses broad-spectrum antimicrobial activity and is used clinically as a disinfectant. We evaluated the disinfectant properties and safety of PVP-I for use as a contact lens solution. The concentrations of PVP-I required to reduce the number of Staphylococcus aureus or Candida albicans by 3 log units were lower than were those of hydrogen peroxide, polyhexamethylene biguanide (PHMB), and benzalkonium chloride (BAK). The cytotoxicity of PVP-I for cultured human corneal epithelial (HCE) cells was less than that of the other three agents. The safety margin for PVP-I was thus greatest among the tested compounds. PVP-I appears suited for use as a contact lens disinfectant.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Contact Lens and Anterior Eye - Volume 29, Issue 2, May 2006, Pages 85–91
Journal: Contact Lens and Anterior Eye - Volume 29, Issue 2, May 2006, Pages 85–91
نویسندگان
Ryoji Yanai, Naoyuki Yamada, Kiichi Ueda, Motoharu Tajiri, Toru Matsumoto, Keiji Kido, Shigeru Nakamura, Fumio Saito, Teruo Nishida,