Peak stepping cadence is associated with leg vascular compliance in young adults

ObjectivesTo test the hypothesis that volume or intensity of daily ambulatory activity would associate with greater large artery compliance in healthy untrained adults.DesignCross-sectional study.MethodsForty-five recreationally active young adults (22 ± 3 yr, 51% women) wore an accelerometer for 5.3 ± 1.3 days for determination of average daily steps (volume) and 30-min peak stepping cadence (intensity; average steps per min for the 30 highest min in a day). Arterial compliance of the common carotid artery, superficial femoral artery (SFA), and popliteal artery was estimated using Doppler ultrasound. Data were analyzed using correlational analysis and analysis of covariance.ResultsAverage daily steps and peak stepping cadence was 8957 ± 3422 steps per day and 97 ± 24 steps per min, respectively. Weight was the main independent predictor of daily steps (r2 = 0.13, p = 0.01) and peak stepping cadence (r2 = 0.17, p < 0.01). After adjusting ambulatory activity for weight, SFA compliance was positively correlated with peak stepping cadence (r = 0.53, p < 0.01) but not with daily steps (r = 0.23, p > 0.05). No other correlations were found between ambulatory activity and carotid or popliteal artery compliance (p > 0.05). Adults with peak stepping cadence ≥ 102 steps per min had greater carotid (1.26 ± 0.08 vs. 1.57 ± 0.09 mm2 kPa−1; p = 0.01) and SFA compliance (0.43 ± 0.03 vs. 0.54 ± 0.03 mm2 kPa−1; p = 0.04) than adults with lower stepping cadence.Conclusions“Brisk” stepping cadence during daily ambulation is associated with greater leg vascular compliance. These results support the promotion of accumulating 30 min of “brisk” walking per day as a strategy to improve vascular health.