کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2706666 1144823 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Topographic Patterns and Stroke Subtypes According to Progressive Motor Deficits in Lacunar Syndrome
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مغز و اعصاب بالینی
پیش نمایش صفحه اول مقاله
Topographic Patterns and Stroke Subtypes According to Progressive Motor Deficits in Lacunar Syndrome
چکیده انگلیسی

Although progressive hemiparesis occurs frequently in acute ischemic stroke, the topography and mechanisms associated with progressive motor deficit (PMD) remain unclear. The aim of this study was to identify the differences in PMD according to lesion location and the presumed underlying pathogenesis in patients with lacunar motor syndrome. Consecutive patients experiencing acute lacunar motor syndrome within 24 hours of stroke onset were included. Topographic patterns, risk factors, and presumed stroke mechanisms were compared between patients with PMD and those without PMD. Of the 168 patients in the study group, 47 (28.0%) had PMD. Baseline National Institutes of Health Stroke Scale score (P = .034) and female sex (P = .005) were associated with PMD on univariate analysis. Deep perforating artery infarct was more frequently associated with PMD (35.8%) compared with large artery disease (27.3%) and cardioembolism (5.3%). Multiple logistic analysis found that deep perforating artery infarct was independently associated with PMD (odds ratio, 2.87; 95% confidence interval, 1.26-6.5; P = .012). Deep perforating artery infarct is the major cause of PMD. In patients with lacunar syndrome, the pattern of PMD varies according to the location and etiology of stroke.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Stroke and Cerebrovascular Diseases - Volume 20, Issue 4, July–August 2011, Pages 352–356
نویسندگان
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