کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2710638 1145008 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Pregnancy and Puerperium-Related Strokes in Asian Women
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مغز و اعصاب بالینی
پیش نمایش صفحه اول مقاله
Pregnancy and Puerperium-Related Strokes in Asian Women
چکیده انگلیسی

BackgroundDespite an increased risk of stroke in pregnancy and puerperium, the overall incidence of the condition in this population is low. Therefore, there is limited data pertaining to these patients particularly from Asian countries. Our objective was to describe the risk factors and outcomes of 110 pregnancy-related ischemic strokes from 5 Asian countries.MethodsData were collected by retrospective chart review in most cases and prospectively in the rest. Inclusion criteria for this subanalysis were women, pregnant or within 1-month postpartum, presenting to the study center with acute ischemic stroke (arterial or venous) confirmed by neuroimaging. Intracranial hemorrhages other than the ones associated with cerebral venous thrombosis or hemorrhagic infarct were excluded. Risk factors were diagnosed based on already published criteria. Outcomes were measured using modified Rankin score. Statistical analysis was done using Statistical Package for Social Sciences version 19.0.ResultsIn all, 110 women with mean age of 27.94 years presented with pregnancy-related ischemic strokes; 58.2% of the strokes occurred postpartum and 49.1% were secondary to cerebral venous thrombosis. Venous strokes were significantly more likely to occur postpartum compared with arterial strokes (P = .01), to have abnormal “hypercoagulable panel result on admission” (P < .001), less likely to have traditional stroke risk factors (P < .001), to have hemorrhagic conversion of stroke (P < .001), and to have lesser stroke severity and better functional outcome at 3 months (P < .001 for each).ConclusionCerebral venous thrombosis is a significant contributor to pregnancy-related strokes in Asian women. Both traditional and pregnancy-specific risk factors should be addressed to control ischemic stroke risk in these women.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Stroke and Cerebrovascular Diseases - Volume 22, Issue 8, November 2013, Pages 1393–1398
نویسندگان
, , , , , , , , ,