Endothelial Dysfunction in PCOS: Role of Obesity and Adipose Hormones

These data suggest that young women with PCOS have evidence for altered endothelial function. Adverse endothelial parameters were correlated with insulin resistance and lower adiponectin. Both insulin resistance and adiponectin appear to be important parameters. It is hypothesized that the type of fat distribution may influence these factors. © 2006 Elsevier Inc. All rights reserved.