Cutaneous Lymphomas

The skin is the most common site of extranodal non-Hodgkin lymphoma, with a yearly incidence approaching 1 per 100,000 individuals in the United States. Skin lymphomas are classified broadly into cutaneous T-cell lymphoma (CTCL) and cutaneous B-cell lymphoma (CBCL). Within these broad categories, multiple unique pathologic entities exist with a wide array of natural histories and treatment options. Radiotherapy plays an important role in the curative treatment of localized CTCL and CBCL and may be used to palliate cutaneous and visceral symptoms associated with advanced disease. This review highlights the role of radiotherapy in the multidisciplinary management of cutaneous lymphoma.