کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2737952 1148119 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Role of Intraoperative Radiation Therapy in Patients With Pancreatic Cancer
ترجمه فارسی عنوان
نقش درمان رادیوتراپی در بیماران مبتلا به سرطان پانکراس
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
چکیده انگلیسی

Intraoperative radiation therapy (IORT) techniques allow for the delivery of high doses of radiation therapy while excluding part or all of the nearby dose-limiting sensitive structures. Therefore, the effective radiation dose is increased and local tumor control potentially improved. This is pertinent in the case of pancreatic cancer because local failure rates are as high as 50%-80% in patients with resected and locally advanced disease. Available data in patients receiving IORT after pancreaticoduodenectomy reveal an improvement in local control, though overall survival benefit is unclear. Series of patients with locally advanced pancreatic cancer also suggest pain relief, and in select studies, improved survival associated with the inclusion of IORT. At present, no phase III data clearly supports the use of IORT in the management of pancreatic cancer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Radiation Oncology - Volume 24, Issue 2, April 2014, Pages 126–131
نویسندگان
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