کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2742307 | 1148597 | 2015 | 6 صفحه PDF | دانلود رایگان |
The incidence of liver disease continues to increase and is now one of the leading causes of death in the United Kingdom. The increasing prevalence of viral hepatitis combined with a surge in the incidence of both alcohol and obesity related liver disease mean that critical care units are increasingly being called upon to assist in managing those with life-threatening complications of end-stage liver disease. Decompensated cirrhosis is not a single organ illness but a complex multisystem disorder typified by impaired immunity, malnutrition and multiorgan failure and presents a significant challenge to the critical care physician. In this article we describe the epidemiology, aetiology, and pathophysiology of decompensated liver disease and describe the management strategies of a range of resulting clinical complications.
Journal: Anaesthesia & Intensive Care Medicine - Volume 16, Issue 4, April 2015, Pages 180–185