کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2763371 1150750 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Rapid injection of rocuronium reduces withdrawal movement on injection
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
پیش نمایش صفحه اول مقاله
Rapid injection of rocuronium reduces withdrawal movement on injection
چکیده انگلیسی

Study ObjectiveTo test whether rapid injection of rocuronium reduces withdrawal movement on injection.DesignRandomized, prospective trial.SettingOperating room in a university hospital.Patients150 ASA physical status I and II patients aged 18 to 60 years, undergoing general anesthesia.InterventionsPatients were randomized to three groups. After undergoing anesthesia induction with thiopental sodium, then 5 seconds later receiving a rubber tourniquet applied to the mid-forearm to stop intravenous (IV) flow by gravity, the pretreatment drug was injected. The tourniquet was held for 15 seconds then released, and 1.0 mg/kg of 1% rocuronium was injected IV. Group C patients (n = 50) were pretreated with 0.1 mL/kg of 0.9% NaCl and then injected with rocuronium slowly within 10 seconds. Group L patients (n = 50) were pretreated with 0.1 mL/kg of preservative-free 1% lidocaine and then injected with rocuronium slowly within 10 seconds. Group R patients (n = 50) were pretreated with 0.1 mL/kg of 0.9% NaCl and then rapidly injected with rocuronium within approximately one second (as quickly as possible).MeasurementsAfter injection of the patient with the study drug, a single anesthesiologist with no knowledge of the study protocol graded each patient's response as follows: 0 = no response; 1 = mild movement limited to the wrist only; 2 = moderate movement involving the elbow and shoulder; and 3 = severe movement involving more than one extremity.Main ResultsGroup C had the most intense and frequent withdrawal response. The frequency and intensity of withdrawal movement was significantly less in Groups L and R than Group C. No significant difference in withdrawal response between Groups L and R was noted.ConclusionsWithdrawal response can be significantly reduced for rocuronium injection without lidocaine pretreatment, simply through rapid injection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Anesthesia - Volume 21, Issue 6, September 2009, Pages 427–430
نویسندگان
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