کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2764333 1567679 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Serial measurements of troponin and echocardiography in patients with moderate-to-severe acute respiratory distress syndrome
ترجمه فارسی عنوان
اندازه گیری های سریالی تروپونین و اکوکاردیوگرافی در بیماران مبتلا به سندرم ديسترس حاد تنفسی حاد و شدید
کلمات کلیدی
ARDS، سندرم ديسترس تنفسی حاد؛ ECG، الکتروکاردیوگرام؛ LV، بطن چپ؛ RV، بطن راست sPAP، فشار خون بالا شریان ریوی سیستولیک؛ تروپونین I؛ TTE، اکوکاردیوگرافی ترانس توراسیک؛ TE
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی

PurposeTo assess the clinical significance of serial troponin I levels (measured in the first 72 hours from admission) in 42 consecutive patients with moderate-to-severe acute respiratory distress syndrome (ARDS). Echocardiography and electrocardiogram testings were serially performed in the time window.Materials and methodsTroponin I was measured every 12 hours in the first 72 hours from intensive care unit (ICU) admission. Echocardiography and electrocardiogram testings were serially performed in the same time window to clinically interpret Tn I levels.ResultsPatients with admission positive Tn I (38.1%) showed higher values of systolic pulmonary hypertension (P = .013) associated with significantly lower values of tricuspid annular plane excursion (P = .011). Twenty-five patients (25/42, 59.5%) exhibited positive peak Tn I and at second echocardiographic assessment exhibited significant lower tricuspid annular plane excursion values (P = .005). At stepwise regression analysis the following variables were an independent predictor for in-ICU mortality: Pco2 (OR 1.08, 95% CI 1.011-1.161, P = .023), systolic pulmonary arterial hypertension (OR 0.83, 95% CI 0.701-0.977, P = .002), log peak Tn I (OR 3.56, 95% CI 1.045-12.132, P = .042).ConclusionsIn moderate-to-severe ARDS, serial troponin I assessment together with echocardiography evaluation helped to identify a subgroup at higher risk for in-ICU death. Moreover, troponin release can be related to right ventricular dysfunction, thus highlighting the clinical role of echocardiography in ARDS patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Critical Care - Volume 33, June 2016, Pages 132–136
نویسندگان
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