Role of remifentanil in labour analgesia

SummaryAlthough epidural analgesia is considered to be the most effective form of pain relief for women in labour, it may not be available to, refused by or contraindicated in some parturients. In this group of patients, systemic remifentanil shows promise as a clinically useful alternative. This review summarizes the evidence for the safety and efficacy of remifentanil when used as a labour analgesic, and reviews the literature regarding its dosing regimen and maternal and foetal/neonatal side effects. Large randomized prospective trials are required before it may be recommended for routine use in labouring women.