Frecuencia y características del síndrome metabólico y de la resistencia a la insulina en familiares de primer grado de personas con diabetes mellitus tipo 1

The frequency of MS in child and adolescent FDR1 was similar to that found in the general population according to studies using similar definitions of MS. In contrast, the frequency of MS in adults was lower than that reported in Cuba for the first-degree relatives of patients with type 2 diabetes. IR was not only associated with MS in first-degree relatives. The association of IR with the presence of GADA may reflect the fact that β cell hyperactivity increases autoantigen expression.