Nuevas señales en pubertad: sistema KiSS-1/GPR54

Indeed, in the last months, KiSS-1 has been proven to be a major physiological gatekeeper of gonadoliberin (Gn-RH) neurons and, hence, of the reproductive axis. The present review comprehensively describes the major features of the KiSS-1 system, with special emphasis on its putative role as a major regulator of mammalian puberty.