Acidosis láctica, en relación con insuficiencia renal aguda y metformina, tratada con hemodiálisis con bicarbonato

Lactic acidosis is a rare entity. Mortality is approximately 50%. Lactic acidosis is characterized by metabolic acidosis with elevated blood lactate and anion gap. We present a case of lactic acidosis in a diabetic woman under treatment with metformin. The patient developed acute renal failure due to dehydration and diarrhea. Treatment with continuous venovenous hemodialysis was successful with clinical improvement and recovery of renal function. We describe the case and review the pathophysiological causes and prognosis of this infrequent and severe complication.