The role of cytokines and pathogen recognition molecules in fungal keratitis - Insights from human disease and animal models

► The epidemiology and clinical characteristics of fungal keratitis and its global impact on blindness and visual impairment. ► Anti-microbial defense at the ocular surface. ► Innate and adaptive immune responses during fungal keratitis. ► Potential targets for immunomodulatory therapy to limit host-cell mediated tissue damage during fungal keratitis.