Peptides of the adipokinetic hormone/red pigment-concentrating hormone family with special emphasis on Caelifera: Primary sequences and functional considerations contrasting grasshoppers and locusts

The presented work is a hybrid of an overview and an original research paper. First, we review briefly the structure, biosynthesis, release, mode of action and function of those peptides that constitute the adipokinetic/red pigment-concentrating family. Second, we collate the data on primary sequences available for caeliferan orthoptera, i.e. grasshoppers and locusts, and add a number of new data from previously unpublished work. The data are interpreted in conjunction with morphological and molecular biology data with respect to phylogenetic relationships of these various taxa. Finally, we discuss the differences between the adipokinetic response of grasshoppers and locusts to corpus cardiacum extract or synthetic adipokinetic hormone with regard to flight ability, phase polymorphism, age, presence of adipokinetic hormones, lipophorin system and other parameters. It appears that the higher hyperlipaemic response is always correlated with pronounced flight ability.