کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2804382 1156869 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Impact of differences in glucose tolerance on the prevalence of a negative insulinogenic index
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Impact of differences in glucose tolerance on the prevalence of a negative insulinogenic index
چکیده انگلیسی

ObjectiveTo determine the prevalence of a negative insulinogenic index (change in plasma insulin/change in plasma glucose from 0 to 30 min) from an oral glucose tolerance test according to glucose tolerance category.Materials and MethodsData from the San Antonio Heart Study (n = 2494), Japanese American Community Diabetes Study (JACDS; n = 594) and Genetics of NIDDM Study (n = 1519) were examined. Glucose tolerance was defined by ADA criteria.ResultsIn the combined cohort, the prevalence of a negative insulinogenic index was significantly higher in diabetes 20/616 (3.2%) compared to normal glucose tolerance 43/2667 (1.6%) (p < 0.05). Longitudinally, in the JACDS cohort, the prevalence did not change from baseline (3/594; 0.5%) to 5 (4/505; 0.7%) and 10 years (8/426; 1.9%) (p = 0.9) and no subject had a repeat negative insulinogenic index.ConclusionsA negative insulinogenic index occurs at a low prevalence across glucose tolerance categories although more often in diabetes, but without recurrence over time.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Diabetes and its Complications - Volume 27, Issue 2, March–April 2013, Pages 158–161
نویسندگان
, , , , , , , , , , ,