کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2815475 1159873 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
p38 MAP kinases in the heart
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
p38 MAP kinases in the heart
چکیده انگلیسی

p38 kinases are members of the mitogen-activated protein kinases (MAPK) with established contribution to a wide range of signaling pathways and different biological processes. The prototypic p38 MAPK, p38α was originally identified as an essential signaling kinase for inflammatory cytokine production Extensive studies have now revealed that p38s have critical roles in many different tissues far beyond immune regulation and inflammatory responses. In this review, we will focus on the structure and molecular biology of p38s, and their specific roles in heart, especially regarding myocyte proliferation, apoptosis, and hypertrophic responses.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 575, Issue 2, Part 2, 10 January 2016, Pages 369–376
نویسندگان
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