کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2816063 1159913 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Towards an understanding of semaphorin signalling in the spinal cord
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
Towards an understanding of semaphorin signalling in the spinal cord
چکیده انگلیسی

Semaphorins are a large family of proteins that are classically associated with axon guidance. These proteins and their interacting partners, the neuropilins and plexins are now known to be key mediators in a variety of processes throughout the nervous system ranging from synaptic refinement to the correct positioning of neuronal and glial cell bodies. Recently, much attention has been given to the roles semaphorins play in other body tissues including the immune and vascular systems. This review wishes to draw attention back to the nervous system, specifically focusing on the role of semaphorins in the development of the spinal cord and their proposed roles in the adult. In addition, their functions in spinal cord injury at the glial scar are also discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 553, Issue 2, 15 December 2014, Pages 69–74
نویسندگان
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