کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2816099 1159915 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs
چکیده انگلیسی


• Different finishing period lengths with α-tocopherol supplementation were studied.
• Genes related to vitamin E metabolism in 2 tissues were studied.
• ABCA1, LPL, APOE, and SREBP1 are significantly regulated in muscle.
• ABCA1, SCARB1, LPL, PPARA, and PPARG are significantly regulated in fat.
• The expression of most of the genes showed a short-term α-tocopherol effect.

The aim of this study was to investigate how different finishing period lengths with α-tocopherol supplementation or alfalfa grazing affect mRNA expression levels of genes related to vitamin E metabolism in L. thoracis (LT) muscle and subcutaneous fat (SF) from lambs of the Rasa Aragonesa breed. Indoors, concentrate-fed light lambs (n = 48) were supplemented with 500 dl-α-tocopheryl acetate/kg concentrate for an average finishing period length of 0 (C), 10.7 (VE10d), 21.2 (VE20d) and, 32.3 (VE30d) days before slaughtering. Simultaneously, 8 lambs with their dams were alfalfa-grazed. The α-tocopherol affected in a short-term the expression of genes in LT muscle (ABCA1, LPL, APOE, and SREBP1) and SF (ABCA1, SCARB1, LPL, and PPARG). On the contrary, PPARA gene expression showed a long-term α-tocopherol effect because the highest levels of PPARA mRNA were found in the VE30d.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 552, Issue 2, 1 December 2014, Pages 225–233
نویسندگان
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