کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2818490 1569862 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Identification of the Plasmodium falciparum rhoptry neck protein 5 (PfRON5)
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
Identification of the Plasmodium falciparum rhoptry neck protein 5 (PfRON5)
چکیده انگلیسی

Gathering knowledge about the proteins involved in erythrocyte invasion by Plasmodium merozoites is the starting point for developing new strategies to control malarial disease. Many of these proteins have been studied in Toxoplasma gondii, where some belonging to the Moving Junction complex have been identified. This complex allows a strong interaction between host cell and parasite membranes, required for parasite invasion. In this genus, four rhoptry proteins (RON2, RON4, RON5 and RON8) and one micronemal protein (TgAMA-1) have been found as part of the complex. In Plasmodium falciparum, RON2 and RON4 have been characterized. In the present study, we identify PfRON5, a ~ 110 kDa protein which is expressed in merozoite and schizont stages of the FCB-2 strain.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 474, Issues 1–2, 15 March 2011, Pages 22–28
نویسندگان
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