کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2824431 1161653 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sequence of plasmid pBS228 and reconstruction of the IncP-1α phylogeny
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
Sequence of plasmid pBS228 and reconstruction of the IncP-1α phylogeny
چکیده انگلیسی

The antibiotic resistance plasmid pBS228 has been completely sequenced, and revealed to be descended from a plasmid virtually identical to the Birmingham IncP-1α plasmid RK2/RP4/RP1. However, it has three additional transposon insertions, one of which is responsible for the extra antibiotic resistances conferred. Loss of kanamycin resistance, which is characteristic of most IncP-1α plasmids, is the result of this insertion. A second transposon causes inactivation of the mating pair formation apparatus, rendering the plasmid non-self-transmissible. Comparison with the published data for other IncP-1α plasmids gives insight into the recent evolutionary history of this group as well as the acquisition and transmission of one of the first ampicillin resistance transposons discovered.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Plasmid - Volume 58, Issue 1, July 2007, Pages 76–83
نویسندگان
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