کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2832317 1163834 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immunogenicity of autologous immunoglobulins: Principles and practices
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی مولکولی
پیش نمایش صفحه اول مقاله
Immunogenicity of autologous immunoglobulins: Principles and practices
چکیده انگلیسی

The immunogenicity of immunoglobulin idiotypes in syngeneic systems is a rather rare phenomenon. Very few studies have attempted to determine the mechanisms underlying the anti-idiotypic response that certain autologous idiotypes can elicit. Furthermore, the studies addressing a possible physiological role for such behaviors are even less. In the present article, the results of the characterization of a highly immunogenic idiotype are reviewed and compared with some related works on the subject. We finally propose a possible immunoregulatory role for idiotypic immunogenicity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Molecular Immunology - Volume 44, Issue 11, April 2007, Pages 3076–3082
نویسندگان
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