Seasonal acclimatization to the hot summer over 60 days in the Republic of Korea suppresses sweating sensitivity during passive heating

• This study was to determine the central mechanisms involved in sweating after seasonal acclimatization.
• Sweat responses, body temperature, basal metabolic rate were measured.
• Blunt the central sudomotor mechanisms following seasonal acclimatization.

The main objective of this study was to determine the central mechanisms involved in suppression of thermal sweating after seasonal acclimatization (SA) during passive heating (immersing the legs in 43 °C hot water for 30 min). Testing was performed in July (before-SA) and August (after-SA) [25.2±2.2 °C, 73.9±10.3% relative humidity (RH), Cheonan (Chungnam,126° 52′N, 33.38′E), in the Republic of Korea. All experiments were carried out in an automated climatic chamber (25.0±0.5 °C and RH 60.0±3.00%). Twelve healthy men (height, 174.6±5.40 cm; weight, 65.4±5.71 kg; age, 22.7±2.90 yr) participated. The local sweat onset time was delayed in the after-SA compared to that in the before-SA (p<0.001). The local sweat rate and whole body sweat loss volume decreased in the after-SA compared to those in the before-SA (p<0.001). In addition, evaporative loss volume decreased significantly in the after-SA compared to that in the before-SA [chest, upper-back, thigh and forearm (p<0.001)]. Changes in tympanic temperature and mean body temperature were significantly lower (p<0.05) and the basal metabolic rate decreased significantly in the after-SA compared to those in the before-SA (p<0.001). These results suggest that maintenance of a lower body temperature and basal metabolic rate can occur and blunt the central sudomotor mechanisms following seasonal acclimatization, which suppresses sweating sensitivity.