کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2843442 | 1166095 | 2010 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cytoprotection of vitamin E on hyperthermia-induced damage in bovine mammary epithelial cells
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
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چکیده انگلیسی
The protective effects of vitamin E (VE) against hyperthermia-induced damage in bovine mammary epithelial cells (BMEC) were studied. The structure of BMEC membrane was damaged by hyperthermia treatment. The VE (25 nmol/ml) efficiently increased cell viability and attenuated morphological damages in hyperthermia-treated BMEC. Compared with the control, VE significantly reduced lactate dehydrogenase leakage and malondialdehyde formation in hyperthermia-treated BMEC. Meanwhile, superoxide dismutase activity was increased significantly in the presence of VE. It is inferred that VE displayed cytoprotective effects on hyperthermia-induced damage in BMEC through increasing intracellular antioxidant levels and decreasing lipid peroxidation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Thermal Biology - Volume 35, Issue 5, July 2010, Pages 250–253
Journal: Journal of Thermal Biology - Volume 35, Issue 5, July 2010, Pages 250–253
نویسندگان
Hong-Yun Liu, Ke Zhao, Miao-Miao Zhou, Cong Wang, Jun-An. Ye, Jian-Xin Liu,