Neurophysiological aspects of the long-term adaptation to cold in mammals: The role of central and peripheral thermoreceptors

The results of many years of experimental studies of the effects of the organism's long-term adaptation to cold and noradrenaline on the impulse activity of the central hypothalamic and peripheral skin thermoreceptors are summarized. Considered are the issues pertaining to the involvement of the sympathetic nervous system in the formation of the adaptive changes in the regulatory characteristics of thermal homeostasis and also the contribution of the different components of thermoreceptors activity to the formation of effector responses. The role of various types of thermoreceptors in the formation of thermal sensation is discussed.