کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2844593 1166351 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
From bedside to bench and back again: A 30-year saga
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
پیش نمایش صفحه اول مقاله
From bedside to bench and back again: A 30-year saga
چکیده انگلیسی

My work (Mark S. Gold) began in the 70s looking for the mechanisms of drug reinforcement and withdrawal. Through observation and experience, drugs of abuse and the drive for food appeared to be quite related. As pioneered by Bart Hoebel, food can become an object of desire and act in most respects as a drug of abuse. The Gold lab is investigating working models for pathological attachment to eating and food addiction. New pharmacological treatments which interfere with food reinforcement may be the next step.

Research highlights
► Clinicians look to researchers for laboratory models and testable hypotheses.
► Withdrawal and abstinence similarities.
► Food, sugar and addiction recovery.
► Rat model of binge eating on sugar and sugar/fat solutions.
► Reward, relapse, and common hedonic mechanisms

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physiology & Behavior - Volume 104, Issue 1, 25 July 2011, Pages 157–161
نویسندگان
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