کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2845259 | 1166385 | 2009 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
‘Liking’ and ‘wanting’ food rewards: Brain substrates and roles in eating disorders
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کلمات کلیدی
Opioid - opioidVentral pallidum - pallidum درشتEating disorders - اختلالات خوردنAddiction - اعتیاد Bulimia - بولیمیاAnorexia - بیاشتهاییFood - خوراک یا غذاDopamine - دوپامینIngestive behavior - رفتار بدخواهBrainstem - ساقه مغزPleasure - لذتNucleus accumbens - هسته accumbensparabrachial nucleus - هسته parabrachialReward - پاداش
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
فیزیولوژی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
What brain reward systems mediate motivational ‘wanting’ and hedonic ‘liking’ for food rewards? And what roles do those systems play in eating disorders? This article surveys recent findings regarding brain mechanisms of hedonic ‘liking’, such as the existence of cubic-millimeter hedonic hotspots in nucleus accumbens and ventral pallidum for opioid amplification of sensory pleasure. It also considers brain ‘wanting’ or incentive salience systems important to appetite, such as mesolimbic dopamine systems and opioid motivation circuits that extend beyond the hedonic hotspots. Finally, it considers some potential ways in which ‘wanting’ and ‘liking’ might relate to eating disorders.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physiology & Behavior - Volume 97, Issue 5, 14 July 2009, Pages 537–550
Journal: Physiology & Behavior - Volume 97, Issue 5, 14 July 2009, Pages 537–550
نویسندگان
Kent C. Berridge,