کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2845955 1571215 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mechanotransduction and the crayfish stretch receptor
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
پیش نمایش صفحه اول مقاله
Mechanotransduction and the crayfish stretch receptor
چکیده انگلیسی

Mechanotransduction or mechanosensitivity is found in almost every cell in all organisms from bacteria to vertebrates. Mechanosensitivity covers a wide spectrum of functions from osmosensing, cell attachment, classical sensory mechanisms like tactile senses in the skin, detection of sound in hair cells of the hearing apparatus, proprioceptive functions like recording of muscle length and tension in the muscle spindle and tendon organ, respectively, and pressure detection in the circulation etc. Since most development regarding the molecular aspects of the mechanosensitive channel has been made in nonsensory systems it is important to focus on mechanosensitivity of sensory organs where the functional importance is undisputed. The stretch receptor organ of the crustaceans is a suitable preparation for such studies. The receptor organ is experimentally accessible to mechanical manipulation and electrophysiological recordings from the sensory neuron using intracellular microelectrode or patch clamp techniques. It is also relatively easy to inject substances into the neuron, which also makes the neuron accessible to measurements with fluorescent techniques. The aim of the present paper is to give an up to date summary of observations made on the transducer properties of the crayfish stretch receptor (Astacus astacus and Pacifastacus leniusculus) including some recent unpublished findings. Finally some aspects on future line of research will be presented.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physiology & Behavior - Volume 92, Issues 1–2, September 2007, Pages 21–28
نویسندگان
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