کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2846584 | 1166430 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Interaction between nociceptin/orphanin FQ (N/OFQ) and GABA in response to feeding
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
فیزیولوژی
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چکیده انگلیسی
Nociceptin/orphanin FQ (N/OFQ) and gamma aminobutyric acid (GABA) agonists have been shown to increase feed intake in mammals and birds. In this study, the effect of intracerebroventricular (icv) injection of the potent NOP receptor agonists Nociceptin (1–13) NH2, the GABAA receptor antagonist bicuculline, and the GABAA receptor agonist muscimol on feed intake in cockerels was investigated. The icv injection of N/OFQ and muscimol increases feed intake. The effect of N/OFQ on feed intake was strongly blocked by the injection of bicuculline whereas the effect of muscimol was stimulated by N/OFQ. These results suggest that N/OFQ may act at GABAA receptors or increases overflow of GABA in the brain of chickens to stimulate feeding.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physiology & Behavior - Volume 89, Issue 3, 30 October 2006, Pages 410–413
Journal: Physiology & Behavior - Volume 89, Issue 3, 30 October 2006, Pages 410–413
نویسندگان
S. Tajalli, H. Jonaidi, M. Abbasnejad, D.M. Denbow,