The Interaction Between Human Urotensin II and Vasodilator Agents in Human Internal Mammary Artery With Possible Clinical Implications

Human urotensin II is a potent vasoconstrictor in human IMA. Calcium antagonists and GTN relax the contraction caused by hU-II with different potencies. However, calcium antagonists are more effective than GTN in preventing the contraction induced by hU-II. These findings may have clinical implications in CABG.