MicroRNA Prognostic Signature for Nodal Metastases and Survival in Esophageal Adenocarcinoma

These results suggest miRNA expression profiling could provide prognostic utility in staging esophagus cancer patients and treatment planning with endoscopic and neoadjuvant therapies. The alterations of specific miRNAs may further elucidate steps in the metastatic pathway and allow for development of targeted therapy.