کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2878437 | 1573956 | 2010 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Controversies in Oral Antiplatelet Therapy in Patients Undergoing Aortocoronary Bypass Surgery
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Oral antiplatelet therapy with aspirin and clopidogrel is a major strategy to prevent thrombotic events in patients with acute coronary syndromes and patients undergoing percutaneous coronary interventions. Although this therapy is associated with both short- and long-term clinical efficacy, irreversible platelet inhibition and ischemic events associated with premature withdrawal especially in patients treated with drug-eluting stents constitute a particular limitation in patients undergoing surgery. The current review article is focused on the central role of platelets in the occurrence of ischemic events, the significance of antiplatelet therapy, the potential hazards of drug withdrawal in patients needing coronary artery bypass grafting, and future perspectives.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Annals of Thoracic Surgery - Volume 90, Issue 3, September 2010, Pages 1040-1051
Journal: The Annals of Thoracic Surgery - Volume 90, Issue 3, September 2010, Pages 1040-1051
نویسندگان
Elisabeth MD, Helfried MD, Udaya S. PhD, Paul A. MD,