Alveolar Macrophage Secretory Products Augment the Response of Rat Pulmonary Artery Endothelial Cells to Hypoxia and Reoxygenation

Alveolar macrophages drive the development of lung reperfusion injury, by enhancing the production of proinflammatory chemokines from endothelial cells, which impart a degree of positive feedback on alveolar macrophages.