Prognostic Significance of a Histologic Subtype in Small Adenocarcinoma of the Lung: The Impact of Nonbronchioloalveolar Carcinoma Components

Small adenocarcinomas can be classified into two categories. The first category is a minimal or non-BAC adenocarcinoma that shows aggressive biological behavior. The second category is a mixed BAC, which demonstrates less invasive or aggressive biological behavior than the minimal or non-BAC type, with the degree of invasiveness being associated with the size of the non-BAC component.